Table 1.
Summary of lipid species identified from individual TLC bands of urinary microvesicles and exosomes using MALDI-TOF MS.
| Lipid class | Lipid species | Urinary microvesicles | Urinary exosomes | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Band1 (MV1) | Band2 (MV2) | Band3 (MV3) | Band1 (Exo1) | Band2 (Exo2) | Band3 (Exo3) | Band4 (Exo4) | Band5 (Exo5) | ||
| Sphingolipid | Ceramides (Cer) | + | + | + | + | + | + | + | + |
| Ceramide phosphates (CerP) * | − | − | − | + | + | + | + | + | |
| Hexosyl ceramides (HexCer) | + | + | + | + | + | + | + | + | |
| Hexosyl sphingoid bases (HexSph) * | − | − | − | − | − | + | − | + | |
| Lactosyl ceramides (LacCer) * | − | − | − | − | + | − | − | − | |
| Lactosyl sphingoid bases (LacSph) | + | + | − | + | − | + | + | − | |
| Mannosyl-di-PI-ceramides (M(IP)2 C) * | − | − | − | − | + | − | − | − | |
| Mannosyl-PI-ceramides (MIPC) | + | − | − | + | + | − | + | + | |
| Sphingomyelins (LysoSM) | + | + | + | − | − | − | + | + | |
| PE-ceramides (PE-Cer) | + | + | + | + | + | − | + | + | |
| PI-ceramides (PI-Cer) # | + | − | + | − | − | − | − | − | |
| Sulfatides hexosyl ceramide (SHexCer) * | − | − | − | − | − | − | − | + | |
| Sulfatides hexosyl sphingoid bases (SHexSph) * | − | − | − | − | + | + | + | + | |
| Sphingomyelins (SM) | + | − | + | − | − | − | + | − | |
| Fatty acid | Acyl carnitines (CAR) | + | + | + | + | + | − | + | + |
| Acyl CoA’s (CoA) | + | − | + | + | + | + | + | + | |
| Cardiolipins (CL) | + | − | − | + | − | − | − | − | |
| Cholesteryl esters (CE) | + | + | + | − | − | − | + | + | |
| Fatty acids (FA) | + | + | + | + | + | + | + | + | |
| Wax esters (WE) | + | + | + | + | + | + | + | + | |
| Glycerolipid | Di(acyl|alkyl)glycerols (DG) | + | + | + | + | + | + | + | + |
| Mono(acyl|alkyl)glycerols (MG) # | + | − | − | − | − | − | − | − | |
| Monogalactosyldiacylgylcerols (DGDG) | + | + | + | + | + | + | + | + | |
| Monogalactosyldiacylgylcerols (MGDG) | + | + | + | + | − | + | + | + | |
| Sulfoquinovosyldiacylglycerols (SQDG) | + | + | + | + | + | + | + | + | |
| Tri(acyl|alkyl)glycerols (TG) | + | + | + | + | + | + | + | + | |
| Phospholipid | Lysophosphatidic acids (LPA) | + | + | − | + | + | − | + | + |
| Lysophosphatidylcholines (LPC) | + | + | + | + | + | + | + | + | |
| Lysophosphatidylethanolamines (LPE) | + | + | + | + | + | − | + | + | |
| Lysophosphatidylglycerols (LPG) | + | + | + | + | + | + | + | + | |
| Lysophosphatidylinositols (LPI) | − | + | + | + | + | + | + | + | |
| Lysophosphatidylinositol phosphates (LPIP) | + | + | + | + | + | + | + | + | |
| Lysophosphatidylserines (LPS) | + | + | + | − | + | + | − | − | |
| Phosphatidic acid (PA) | + | + | + | + | + | + | + | + | |
| Phosphatidylcholines (PC) | + | + | + | + | + | + | + | + | |
| Phosphatidylethanolamine (PE) | + | + | + | − | + | − | − | − | |
| Phosphatidylglycerols (PG) | + | + | + | + | + | + | + | + | |
| Phosphatidylinositols (PI) | + | + | + | + | + | + | + | + | |
| Phosphatidylinositol phosphates (PIP) | + | + | + | + | + | + | + | + | |
| Phosphatidylserines (PS) | + | + | + | + | + | + | + | + | |
Symbols used: +Found; −Not found; *Present only in exosomes; #Present only in microvesicles.