Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Sep 25;9:13892. doi: 10.1038/s41598-019-50456-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Whole genome database searches revealed that ICEKp2 occurred in two outbreaks of carbapenem resistant K. pneumoniae in the US, in isolates with and without ICEKp1. The core genome tree shows the sequence type (ST) and capsule synthesis loci (KL) of all isolates and the study strain HS11286. The occurrence and co-occurrence of ICEKp1 and ICEKp2 (marker genes) are shown in the heat map to the right (black = present, grey = absent). The virulence associated genes rmpA and rmpA2 were also included in analysis to determine their co-relation with the presence/absence of ICEKp1 and ICEKp2. For US isolates, the shape indicates the year of isolation: circles for 2013 and diamonds for 2014, and shading indicates that the strain was part of an outbreak (open shapes were not outbreak associated). The scale bar shown at the bottom left represents the average number of substitutions per site.