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. 2019 Sep 25;9:13845. doi: 10.1038/s41598-019-49970-9

Table 3.

Comparison of our proposed MPBG biomarkers with state-of-the-art methods based on s-MRI and d-MRI using a similar ADNI2 dataset.

Method Subjects Feature Classifier Classification ACC
CN eMCI lMCI AD CN/AD eMCI/lMCI
Nir et al.93 44 74 39 23 Tractography SVM 84.9% n/a
Prasad et al.60 50 74 38 38 Connectivity network SVM 78.2% 63.4%
Zhan et al.94 n/a 73 39 n/a Connectivity network SLG n/a 65.0%
Maggipinto et al.96 50 22 18 50 Voxel-based RF 87.0% n/a
La Rocca et al.95 52 85 38 47 Connectivity network RF 83.0% n/a
MPBG hippocampus 62 65 34 38 Patch-based LDA 88.1% 68.8%
MPBG Subiculum 62 65 34 38 Patch-based LDA 86.5% 70.8%

All results are expressed in percentage of accuracy.

LDA = Linear Discriminant Analysis,

SLG = Sparse Logistic Regression,

SVM = Support Vector Machine,

RF = Random Forest.