TABLE 1.

[³⁵S]GTPγS binding induced by WIN55212-2 (10 μM) in different areas of WT and maLPA₁-null mice, calculated as percentage over the basal value.

	Stimulation by WIN55212-2 (%)
Brain region	WT	maLPA1-null	p-value
Amygdala	36250	23222	0.06
Cerebellum
White matter	2.315	10713∗	0.001
Gray matter	679149	1377207∗	0.04
Corpus callosum	10820	15011	0.18
Striatum	25418	25523	0.75
Frontal cortex
Layer I–III	21219	36949∗	0.05
Layer IV	18833	23614	0.27
Layer V	22325	28212	0.07
Layer VI	28414	39622∗	0.02
Hippocampus
Dorsal CA1 radiata	37151	34138	0.69
Ventral CA3 radiata	28823	26612	0.51
Internal capsule	5316	3314	0.28
Globus pallidus	1705151	203782	0.21

Data are mean ± SEM values, in percentage of stimulation over the basal (%). The p-values were calculated by the unpaired two-tailed Student’s t test. ^∗p ≤ 0.05. WT(n = 8) and maLPA₁null (n = 8).