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KAJD decreases the levels of serum IgE and proinflammatory cytokines. Blood samples were collected from each mouse, and the levels of serum IgE and cytokines IL-6, IL-10, and IL-12 were quantified by ELISA. ### P < 0.001 compared to the vehicle group. **P < 0.01 and ***P < 0.001 compared to the DNCB-stimulated group. Vehicle, no treatment; DNCB, 2,4-dinitrochlorobenzene; TAC, tacrolimus.
