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. 2019 Sep 5;69(Suppl 2):S133–S139. doi: 10.1093/cid/ciz598

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© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Maximum likelihood whole genome phylogenetic tree of Streptococcus pneumoniae isolates recovered from cerebrospinal fluid. Tree annotation from left to right: vaccine type; serotype; multilocus sequence type; year of admission; vaccine era (pneumococcal conjugate vaccine); phenotypic antibiotic resistance profiles to chloramphenicol, trimethoprim-sulfamethoxazole (SXT), tetracycline, oxacillin, and erythromycin; and the presence/absence of the antibiotic resistance genes catQ (chloramphenicol), folA/ folP (SXT), tetM (tetracycline), PBP (penicillin), and ermB (erythromycin). Abbreviations: C, chloramphenicol; E, erythromycin; OX, oxacillin; PCV, pneumococcal conjugate vaccine; SXT, trimethoprim-sulfamethoxazole; TE, tetracycline.