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. 2019 Sep 19;9:913. doi: 10.3389/fonc.2019.00913

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Copyright © 2019 Garrido, Torres, Vega and Romero.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of NGF and VEGF in a tubular formation assay in matrigel with EA.hy926 cells. Cells were disposed in matrigel and stimulated with NGF (N) and VEGF (V). Upper picture: photography of EA.hy926 cells (4 h of assay), which was analyzed by Image J Angiogenesis Analyzer. Bar charts were obtained from multicellular junctions and polygonal structures or meshes, as the arrows indicate. ^*p < 0.05; ^**p < 0.01; ^***p < 0.001, according to Kruskal Wallis test. Figure obtained from Supplementary Material of Garrido et al. (87) (permission has been obtained).