Table 1.
Characteristics of the Study Subjects.
| KKT (n=35) | Placebo (n=35) | p value*1 | ||
|---|---|---|---|---|
| Sex | Male | 12 ( 34.3) | 10 ( 28.6) | 0.797 |
| Female | 23 ( 65.7) | 25 ( 71.4) | ||
| Age | Mean (SD) | 37.91 (12.13) | 37.89 (12.99) | 0.992 |
| Median [Range] | 35.00 [20.00, 63.00] | 35.00 [22.00, 65.00] | 0.860 | |
| Body temperature | Mean (SD) | 36.89 (0.77) | 37.05 (0.78) | 0.409 |
| Median [Range] | 36.80 [35.20, 39.30] | 36.90 [35.80, 39.30] | 0.514 | |
| Sore throat score on VAS at baseline | Mean (SD) | 46.63 (22.23) | 42.94 (22.20) | 0.490 |
| Median [Range] | 41.00 [9.00, 96.00] | 39.00 [10.00, 90.00] | 0.507 | |
| Impact of sore throat on daily activities | Mild | 10 ( 28.6) | 16 ( 45.7) | 0.400 |
| Moderate | 23 ( 65.7) | 18 ( 51.4) | ||
| Severe | 2 (5.7) | 1 (2.9) | ||
| Final diagnosis | Influenza | 4 (11.4) | 10 (28.6) | 0.192 |
| Pharyngitis | 27 (77.1) | 23 (65.7) | ||
| Tonsillitis | 3 (8.6) | 1 (2.9) | ||
| Sinusitis | 0 (0.0) | 1 (2.9) | ||
| Streptococcal tonsillitis | 1 (2.9) | 0 (0.0) | ||
| Stratified by age | <45 | 24 (68.6) | 25 (71.4) | 1.000 |
| ≥45 | 11 (31.4) | 10 (28.6) | ||
| Stratified by VAS | <50 | 21 (60.0) | 22 (62.9) | 1.000 |
| ≥50 | 14 (40.0) | 13 (37.1) | ||
*1: Categorical variables: Fisher’s exact test, mean: 2 sample t-test, median: Wilcoxon test
KKT: kikyo-to, VAS: Visual Analogue Scale