Table 1.
Cases of rapid-growing non-tuberculosis mycobacteria (rNTM) identified in blood cultures at our institution, 2012-2018.
| Case | Month/Year | Organism | Central line | Line removed | Culture clearance | Antibiotics | Outcome |
|---|---|---|---|---|---|---|---|
| 59-year-old man with ESRD | 09/2018 | M. chelonae | CVC, tunneled | Y | Y | ciprofloxacin and metronidazole for 7 days | Infection resolved |
| 32-year-old woman with “Chronic Lyme disease” | 03/2018 | M. goodii | CVC, port | Y | N | See text | Declined follow-up |
| 70-year-old man with Parkinson’s Disease | 02/2018 | M. mucogenicum | PICC | Y | Y | piperacillin/ tazobactam for 2 weeks | Infection resolved |
| 28-year-old man with Crohn’s disease | 12/2017 | M. mucogenicum | No midline | Y | Y | linezolid for 2 weeks | Infection resolved |
| 27-year-old woman with ESRD | 10/2016 | M. fortuitum complex | CVC, tunneled | Y | Y | ciprofloxacin and clarithromycin, followed by ciprofloxacin and linezolid for 3 months | Infection resolved |
| 70-year-old woman with Crohn’s disease and recurrent urinary tract infections | 08/2016 and 04/2018 | M. fortuitum complex | CVC, PICC | Y | Y* | ciprofloxacin for 2 weeks | Cleared initially but recurred 1.5 years later with eventual clearance after second PICC line removal |
| 31-year-old woman with renal transplant | 02/2016 | M. mucogenicum group | CVC, port | Y | Y | meropenem, unclear duration | Infection resolved |
| 43-year-old woman with native-valve endocarditis | 12/2015 | M. mucogenicum group | PICC | Y | Y | cefepime for 6 weeks | Infection resolved |
| 52-year-old man with HIV and recurrent urinary tract infections | 09/2013 | M. mucogenicum group | PICC | Y | Y | piperacillin/ tazobactam and daptomycin for 4 weeks | Infection resolved |
| 27-year-old woman with sickle cell anemia | 11/2012 | M. mucogenicum group | CVC, internal jugular | Y | Y | ciprofloxacin and linezolid for 2 weeks | Infection resolved |
ESRD= end-stage renal disease, CVC = central venous catheter, PICC = peripherally inserted central catheter, Midline = peripherally inserted catheter, Y = blood cultures were drawn after line was removed and were immediately negative, N = blood cultures were not negative after line removal.
*Two instances (see Outcome).