Date	Event	Description
30 August 2019	New citation required but conclusions have not changed	The previous version of the review assessed evidence in cardiac and non‐cardiac surgery (Blessberger 2018). We split the review according to type of surgery. The current version assesses the evidence only in non‐cardiac surgery. The evidence for cardiac surgery is reported in (Blessberger 2019). We added three new review authors (Sharon Lewis, Michael Pritchard, Lizzy Fawcett). Three review authors (Danyel Azar, Martin Schillinger, Franz Wiesbauer) were not included in this update. We reduced the number of outcomes to improve the manageability and focus of the review. Myocardial ischaemia, supraventricular arrhythmias (except for atrial fibrillation), ventricular extrasystoles, bronchospasm, and cost of care are not included; effect estimates for these can be found in the previous version (Blessberger 2018). We did not conduct meta‐regression or trial sequential analysis. We explored heterogeneity through subgroup analysis, and used sensitivity analysis to explore decisions made as part of the review process. Conclusions remain unchanged
30 August 2019	New search has been performed	We conducted a search for new studies. We included 52 new studies. We excluded three studies that were previously included (Coleman 1980; Marwick 2009; Sandler 1990), and we merged two references that reported the same study; Mangano 1996 is now a secondary reference under Wallace 1998.