TABLE 1.
Susceptibility results of delafloxacin and comparators against K. pneumoniae and P. aeruginosa strains
| Organism and strain | MIC (mg/liter) |
Strain description | ||
|---|---|---|---|---|
| Delafloxacin | Levofloxacin | Ciprofloxacin | ||
| K. pneumoniae | ||||
| 43816a | 0.06 | 0.06 | Wild type | |
| 4105a | 1 | 1 | TEM26, SHV4 | |
| 4110a | 0.5 | 1 | TEM1, SHV1 | |
| 81-1260Aa | 0.06 | 0.06 | CTX-M, AmpC | |
| 1037570 | 0.5 | 1 | 2 | |
| 997613 | 1 | 0.5 | 0.25 | |
| 1002059 | 4 | 1 | 0.5 | |
| 993043 | 0.03 | 0.03 | 0.03 | |
| 1004234 | 0.06 | 0.06 | 0.03 | |
| 1008721 | 0.12 | 0.12 | 0.12 | |
| 1009343 | 0.25 | 0.12 | 0.25 | |
| 1014490 | 0.25 | 0.12 | 0.06 | |
| P. aeruginosa | ||||
| 71 | 1 | 2 | Wild type | |
| 62 | 2 | 4 | Wild type | |
| 65 | 4 | >8 | parC S87L, gyrA T83I | |
| 724 | 0.12 | ≤0.06 | Wild type | |
| 1004586 | 0.5 | 0.5 | 0.12 | |
a
Results for these strains were retrieved from our previous study (8).