TABLE 3.

Mixed-effects model of potential determinants of POS C_min

Variable	Nonmissing data (%)	Univariate analysis		Multivariate analysis
		Estimate ± SE	P value	Estimate ± SE	P value
POS-tablet	100	0.92 ± 0.11	<0.001	1.13 ± 0.18	<0.001
Age	100	0.33 ± 0.07	<0.001	−0.19 ± 0.11	0.07
Body mass index	76	0.11 ± 0.03	0.72
Proton pump inhibitor	76	0.14 ± 0.19	0.47
Mucositis	82	0.11 ± 0.08	0.17
Diarrhea	80	−0.37 ± 0.08	<0.001	−0.30 ± 0.07	<0.001