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IC50 parameters of the β-lactamase inhibitors tazobactam and avibactam against OXA-2 and OXA-681a
| Drug | IC50 (nM) ± SD |
Ratio of IC50 of OXA-681/IC50 of OXA-2 | |
|---|---|---|---|
| OXA-2 | OXA-681 | ||
| Tazobactam | 1.48 ± 0.4761 | 13 ± 1.8302 | 9 |
| Avibactam | 367 ± 24.1150 | 3,050 ± 902.4786 | 8 |
Data represent the means from three independent experiments.
