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Linear mixed-effects analysis of CLR and CLsys versus CLCR for renal impairment subjects
| Compound | Parameter | Mixed-effect model | Mean slope | Lower CI | Upper CI | P value |
|---|---|---|---|---|---|---|
| FEP | CLR | Intercept + CLCR | 1.10 | 0.78 | 1.42 | 2.16E−06 |
| TAZ | 3.62 | 2.42 | 4.83 | 9.41E−06 | ||
| FEP | CLsys | Intercept + CLCR | 0.93 | 0.64 | 1.21 | 3.55E−06 |
| TAZ | 3.00 | 2.03 | 3.96 | 6.28E−06 |
