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Renal impairment group and WCK 4282 dosage
| Group | Impairment category | CLCR (ml/min) | No. of subjects | WCK 4282 dose (g) |
|---|---|---|---|---|
| 1 | Healthy | ≥90 | 24 | 4 (2 FEP and 2 TAZ) |
| 2 | Mild | 60–89 | 6 | 4 (2 FEP and 2 TAZ) |
| 3 | Moderate | 30–59 | 6 | 4 (2 FEP and 2 TAZ) |
| 4 | Severe | <30a | 6 | 2 (1 FEP and 1 TAZ) |
| 5 | ESRD on HD | 6 | 2 (1 FEP and 1 TAZ) |
The subjects were not on dialysis.
