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MICs of β-lactams against S. maltophilia or K. pneumoniae in the presence of β-lactamase inhibitors
| Strain or plasmid | MIC (μg/ml) of β-lactams by inhibitora
|
|||||
|---|---|---|---|---|---|---|
| Ceftazidime |
Imipenem |
Aztreonam |
||||
| − | +AVI (4 mg/liter) | − | +REL (4 mg/liter) | − | +REL (4 mg/liter) | |
| S. maltophilia K279a | 16 | 8 | 128 | 64 | >256 | 8 |
| Ecl8 pUBYT | <0.125 | <0.0625 | ||||
| Ecl8 pUBYT KPC-2 | 16 | 0.125 | 64 | 0.5 | ||
| Ecl8 pUBYT KPC-3 | 128 | <0.125 | 16 | <0.125 | ||
| Ecl8 pUBYT KPC-4 | 128 | 1 | 0.5 | 0.125 | ||
AVI, avibactam; REL, relebactam; −, no inhibitor present.
