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(A) Mouse survival curves representing the toxicity of ASB (50 to 400 mg/kg). We used 10 mice for each group. (B) Mouse survival curves representing the therapeutic effects of MEM (2.5 mg/kg) or ASB (100 mg/kg) used alone or in combination. Mice were intraperitoneally injected with SMB-1-producing E. coli (E. coli ATCC 25922 carrying pCL-SMB-1) (107 CFU). We used 10 mice for each group. The groups were analyzed using a Mantel-Cox test.
