TABLE 3.
Case ID | Antifungal(s) to which patient was exposeda
|
Time of first terbinafine exposure (yr)b
|
No. of treatment courses with terbinafine (wks of treatment) |
|||
---|---|---|---|---|---|---|
Topical | Systemic | Topical | Systemic | Topical | Systemic | |
1 | Terbinafine | Terbinafine | NA | 2017 | 0 (0) | 1 (NA) |
2 | None | Terbinafine | — | 2014 | 0 | 1 (2) |
3 | Terbinafine, amorolfine, ketoconazole | Terbinafine, itraconazole | NA | 2013 | 6c (8) | 2 (24) |
4 | Terbinafine, amorolfine, ciclopirox | Terbinafine, itraconazole, fluconazole | 2004 | 2010 | 3 (7) | 3 (53) |
5 | Terbinafine, ketoconazole | Terbinafine, itraconazole | 2010 | 2015 | 9c (20) | 2 (6) |
6 | Terbinafine | Terbinafine, itraconazole | 2014 | 2015 | 3 (8) | 2 (17) |
7 | Amorolfine | Terbinafine, fluconazole, itraconazole, griseofulvin | NA | 2000 | NA (NA) | 3 (36) |
8 | Terbinafine, amorolfine, ketoconazole | Terbinafine, itraconazole | 2012 | 2005 | 2 (24) | 3 (28) |
9 | None | Terbinafine, itraconazole | — | 2015 | 0 (0) | 1 (NA) |
10 | NA | Terbinafine, itraconazole | NA | Before 1990 | NA (NA) | NA (>104) |
11 | Terbinafine, miconazole-hydrocortisone combination | Terbinafine, itraconazole | 2017 | 2017 | 2 (10) | 3 (28) |
12 | Terbinafine, amorolfine, ketoconazole | Terbinafine, itraconazole, griseofulvin | 2009 | 2008 | NA (NA) | 2 (24) |
13 | Terbinafine | Terbinafine | 2010 | 2014 | NA (NAd ) | NA (NA) |
14 | Terbinafine | Terbinafine, itraconazole | 2018 | 2018 | 1 (16) | 1 |
NA, not available.
—, no first-exposure year, since topical terbinafine was not used.
Two of the treatment courses consisted of one application only of terbinafine hydrochloride.
Several treatment courses (2 to 4 weeks) in a 2-year period.