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. 2019 Sep 23;63(10):e01126-19. doi: 10.1128/AAC.01126-19

TABLE 3.

Prior exposure to antifungal therapy for patients with non-wild-type Trichophyton isolates

Case ID Antifungal(s) to which patient was exposeda
Time of first terbinafine exposure (yr)b
No. of treatment courses with terbinafine (wks of treatment)
Topical Systemic Topical Systemic Topical Systemic
1 Terbinafine Terbinafine NA 2017 0 (0) 1 (NA)
2 None Terbinafine 2014 0 1 (2)
3 Terbinafine, amorolfine, ketoconazole Terbinafine, itraconazole NA 2013 6c (8) 2 (24)
4 Terbinafine, amorolfine, ciclopirox Terbinafine, itraconazole, fluconazole 2004 2010 3 (7) 3 (53)
5 Terbinafine, ketoconazole Terbinafine, itraconazole 2010 2015 9c (20) 2 (6)
6 Terbinafine Terbinafine, itraconazole 2014 2015 3 (8) 2 (17)
7 Amorolfine Terbinafine, fluconazole, itraconazole, griseofulvin NA 2000 NA (NA) 3 (36)
8 Terbinafine, amorolfine, ketoconazole Terbinafine, itraconazole 2012 2005 2 (24) 3 (28)
9 None Terbinafine, itraconazole 2015 0 (0) 1 (NA)
10 NA Terbinafine, itraconazole NA Before 1990 NA (NA) NA (>104)
11 Terbinafine, miconazole-hydrocortisone combination Terbinafine, itraconazole 2017 2017 2 (10) 3 (28)
12 Terbinafine, amorolfine, ketoconazole Terbinafine, itraconazole, griseofulvin 2009 2008 NA (NA) 2 (24)
13 Terbinafine Terbinafine 2010 2014 NA (NAd ) NA (NA)
14 Terbinafine Terbinafine, itraconazole 2018 2018 1 (16) 1
a

NA, not available.

b

—, no first-exposure year, since topical terbinafine was not used.

c

Two of the treatment courses consisted of one application only of terbinafine hydrochloride.

d

Several treatment courses (2 to 4 weeks) in a 2-year period.