TABLE 2.

Frequency of adverse events of any cause by study day

Adverse event	Frequency (%) in:
	P. falciparum (n = 104) on:			P. vivax (n = 120) on:
	Day 0	Day 1	Day 2	Day 0	Day 1	Day 2
Fever	99.0	56.3	8.8	100	49.2	0.8
Chills	80.8	28.2	2.9	85.8	37.5	0.8
Headache	94.2	58.3	44.1	90.8	53.3	29.2
Nausea	18.3	9.7	3.9	14.2	7.5	0.8
Vomiting	15.4	9.7	1.0	9.2	2.5	0.8
Body pain	84.6	51.5	29.4	75.0	40	10
Fatigue	71.2	34.0	15.7	67.5	30	10.8
Vertigo	31.7	23.3	6.9	23.3	15.8	1.7
Confusion	7.7	4.9	0	1.7	0	0
Insomnia	25.0	6.8	2.0	20.8	3.3	1.7
Deafness	15.4	5.8	0	0	0.8	0
Diarrhea	10.6	7.8	2.0	3.3	1.7	0
Abdominal pain	19.2	13.6	2.9	13.3	11.7	0
Rash	0	0	0	0	0.8	0
Palpitations	1.9	3.9	1.0	0.8	0.8	0
Tachycardia	1.0	0	0	0	0	0