Table 3. Method Accuracy and Precisiona.
pool A |
pool B |
pool C |
pool D |
||||||
---|---|---|---|---|---|---|---|---|---|
interday | intraday | interday | intraday | interday | intraday | interday | intraday | ||
TPrP | measured | 16.5 | 17.1 | 41.4 | 42.3 | 102 | 110 | 246 | 244 |
accuracy | 103 | 107 | 103 | 106 | 102 | 110 | 98.3 | 98 | |
RSD % | 2.4 | 5 | 2.8 | 4 | 1.6 | 7.1 | 1.2 | 1.8 | |
TPhP | measured | 18.4 | 17.5 | 40.4 | 43.5 | 111 | 116 | 264 | 262 |
accuracy | 115 | 109 | 101 | 109 | 111 | 116 | 106 | 105 | |
RSD % | 10.5 | 6.5 | 4.3 | 6.2 | 7.8 | 11 | 3.9 | 3.5 | |
TnBP | measured | 15.3 | 16.9 | 39.9 | 41.6 | 102 | 103 | 246 | 238 |
accuracy | 96 | 106 | 100 | 104 | 102 | 103 | 99 | 95 | |
RSD % | 2.4 | 3.9 | 2.1 | 2.8 | 1.3 | 2.3 | 1 | 3.4 | |
TEP | measured | 14.7 | 16.6 | 40.5 | 40.2 | 99 | 97 | 248 | 244 |
accuracy | 92 | 104 | 101 | 101 | 99 | 97 | 99 | 98 | |
RSD % | 3.1 | 2.7 | 0.6 | 0.3 | 0.7 | 2.1 | 0.7 | 1.6 | |
TEHP | measured | 17.3 | 18.2 | 36.1 | 42.4 | 86 | 103 | 271 | 224 |
accuracy | 108 | 114 | 90 | 106 | 86 | 103 | 108 | 90 | |
RSD % | 8.7 | 9.8 | 11 | 4.2 | 9.7 | 6 | 5.8 | 7.4 | |
TDCPP | measured | 18.1 | 13.7 | 44.5 | 46 | 88 | 86 | 239 | 240 |
accuracy | 113 | 86 | 111 | 115 | 88 | 86 | 96 | 96 | |
RSD % | 9.3 | 10 | 9.8 | 11 | 8.2 | 9.9 | 3.1 | 2.9 | |
TDBPP | measured | 13.8 | 14.8 | 38 | 34.2 | 93 | 88 | 246 | 256 |
accuracy | 87 | 93 | 95 | 86 | 93 | 88 | 98 | 102 | |
RSD % | 9.5 | 5.2 | 6.8 | 10.2 | 4.8 | 8.6 | 1.1 | 1.6 | |
TCPP | measured | 16.1 | 16.4 | 38.8 | 42.4 | 103 | 103 | 246 | 242 |
accuracy | 100 | 102 | 97 | 106 | 103 | 103 | 99 | 97 | |
RSD % | 0.2 | 1.6 | 3.8 | 4.2 | 2.2 | 1.8 | 1 | 2.4 | |
TCP | measured | 16.6 | 16.5 | 42.8 | 43.5 | 103 | 100 | 254 | 241 |
accuracy | 104 | 103 | 107 | 109 | 103 | 100 | 101 | 97 | |
RSD % | 2.8 | 2.3 | 4.6 | 6.1 | 1.8 | 0.1 | 1 | 2.5 | |
TCEP | measured | 15.7 | 16.6 | 40.6 | 41.5 | 102 | 97 | 250 | 232 |
accuracy | 98.3 | 104 | 102 | 104 | 102 | 97 | 100 | 93 | |
RSD % | 1.2 | 2.5 | 1.8 | 2.7 | 1.3 | 1.9 | 0.1 | 5.2 | |
TBOEP | measured | 18.4 | 17.6 | 32.3 | 37.8 | 100 | 97 | 218 | 230 |
accuracy | 115 | 110 | 80.7 | 94.4 | 100 | 97 | 87 | 92 | |
RSD % | 10.4 | 6.9 | 9.1 | 4 | 0.3 | 2.2 | 9.2 | 5.8 | |
RDP | measured | 13.8 | 14.6 | 32.4 | 34.7 | 90 | 88 | 246 | 225 |
accuracy | 86 | 91 | 81 | 87 | 90 | 88 | 98 | 90 | |
RSD % | 9.8 | 6.2 | 9.6 | 9.3 | 7.4 | 8.6 | 1.2 | 7.1 | |
EHDPP | measured | 17.8 | 18.1 | 43.9 | 44.7 | 88 | 108 | 243 | 280 |
accuracy | 111 | 113 | 110 | 112 | 88 | 108 | 97 | 112 | |
RSD % | 12.2 | 9.4 | 6.3 | 8.3 | 8.5 | 5.3 | 2 | 8.5 | |
DAP | measured | 17.2 | 17.2 | 40.8 | 42.6 | 105 | 108 | 241 | 231 |
accuracy | 108 | 108 | 102 | 107 | 105 | 108 | 97 | 92 | |
RSD % | 5.4 | 5.4 | 3.1 | 4.6 | 3.4 | 5.4 | 2.5 | 5.5 | |
DMP | measured | 15.9 | 15.3 | 39.2 | 38.9 | 97 | 97 | 242 | 241 |
accuracy | 99.5 | 95.7 | 97.9 | 97.1 | 97 | 97 | 97 | 96 | |
RSD % | 0.3 | 3 | 1.5 | 2 | 1.8 | 1.8 | 2.3 | 2.6 | |
DHP | measured | 17.2 | 17.5 | 40.3 | 40.4 | 102 | 102 | 246 | 229 |
accuracy | 107 | 109 | 101 | 101 | 102 | 102 | 98 | 92 | |
RSD % | 5.1 | 6.4 | 0.6 | 0.8 | 1.4 | 1.3 | 1.2 | 5.9 | |
DEP | measured | 18.9 | 19.3 | 42.1 | 41.7 | 109 | 99 | 246 | 248 |
accuracy | 118 | 121 | 105 | 104 | 109 | 99 | 98 | 99 | |
RSD % | 12.6 | 14.7 | 2.8 | 3 | 6.2 | 0.5 | 1.2 | 0.5 | |
DBP | measured | 17.7 | 14.1 | 31.9 | 44.7 | 118 | 92 | 261 | 241 |
accuracy | 111 | 88.4 | 79.8 | 112 | 118 | 92 | 104 | 97 | |
RSD % | 7.6 | 8.2 | 13.3 | 8.4 | 12.9 | 5.8 | 3.1 | 2.4 | |
BBP | measured | 14.6 | 14.7 | 35 | 35.4 | 97 | 95 | 260 | 241 |
accuracy | 90.9 | 91.9 | 87.4 | 88.4 | 97 | 95 | 104 | 96 | |
RSD % | 6.4 | 5.7 | 7 | 8.2 | 1.9 | 3.3 | 2.8 | 2.5 | |
TBBPA | measured | 14.3 | 15.4 | 36.4 | 40.5 | 90 | 110 | 238 | 227 |
accuracy | 89.5 | 96.0 | 90.9 | 101 | 90 | 110 | 95 | 91 | |
RSD % | 7.4 | 2.8 | 4.8 | 1 | 7 | 7.1 | 3.3 | 6.5 |
Concentrations for the pools A, B, C, and D are 16, 40, 100, and 250 ng/mL, respectively.