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. 2019 Jul 17;8(15):e011012. doi: 10.1161/JAHA.118.011012

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© 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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mRNA levels of genes associated with cardiac pathology and the glucocorticoid receptor (GR) levels in the heart. Total RNA was isolated from whole hearts of 3‐month‐old male and female control (GRflox) and cardiomyocyte‐specific glucocorticoid receptor knockout mice. Expression levels of β‐myosin heavy chain (A), skeletal muscle α‐actin (B), brain natriuretic peptide (C), were measured by QRT‐PCR. Data represent n=5 mice per sex and genotype. β‐Mhc indicates β‐myosin heavy chain; cCGRkO, cardiomyocyte‐specific glucocorticoid receptor knockout; GR, glucocorticoid receptor; Nppb, brain natriuretic peptide; Ska, skeletal muscle α‐actin. *P<0.05, and ***P<0.001.