Figure 1.

Radial artery transplant model in Mauritian cynomolgus macaques. A, Illustration demonstrating location of radial artery transplantation site in relation to the bifurcation of the brachial artery into the radial and ulnar arteries. The radial and ulnar arteries provide a redundant blood source to hand. B, Representative images of radial artery transplantation before (top) and after (bottom) microsurgical anastomosis of the radial artery graft. C, Illustration demonstrating radial artery transplant model. Monkey 1 represents a major histocompatibility complex (MHC) homozygous animal (brown/brown), and monkey 2 represents an MHC heterozygous animal (brown/green). The radial artery allograft from monkey 1 is transplanted into monkey 2 (homozygous haplomatch), whereas the radial artery allograft from monkey 2 is transplanted into monkey 1 (partial haplomatch). The autograft represents the surgical control in each monkey. D, Representative images of patent (left) and nonpatent (right) radial arteries before vessel explants. The arm with 2 patent vessels demonstrates a brachial artery that divides into the radial and ulnar arteries, which provide blood flow to the distal extremity/hand. In the arm with a nonpatent radial artery, there is no division of the brachial artery and only the ulnar artery can be traced down to hand.