Skip to main content
. 2019 Jul 26;8(15):e012093. doi: 10.1161/JAHA.119.012093

Table 3.

Details of Cases of Morphologic Abnormalities

Case Group Birth Defects Age at Delivery/Underlying Disease Delivery Outcome Superimposed Preeclampsia Antihypertensive Agents Other Drugs
1 A PVS 41 y.o.
Essential hypertension
35w4d
1872 g
Prepregnancy to 4w6d Am 12w0d to 28w0d: LDA
34w5d to 35w0d Me
35w1d to delivery Me, Nif
2 A VSD 36 y.o.
Primary aldosteronism
38w0d
3217 g
Prepregnancy to 6w4d Am 8w3d to 28w0d: LDA
6w5d to 8w0d Hy
8w1d to delivery Am
3 O Low‐lying conus medullaris/hypospadias/inguinal hernia 42 y.o.
Essential hypertension
29w1d
521 g
+ Prepregnancy to 8w2d La 12w6d to delivery: LDA
9w4d to 12w0d Me
12w1d to 12w5d Me, La
12w6d to 17w5d Me, La, Am
17w6d to delivery Me, Am
4 O VSD 38 y.o.
Essential hypertension
RA
25w6d
382 g
Prepregnancy to delivery Nic, La Prepregnancy to delivery: PSL
3w to delivery: LDA
5 O Hypospadias 39 y.o.
Essential hypertension
39w4d
2912 g
+ 8w4d to 30w2d Me None
30w3d to delivery Me, Am
6 N Hypospadias 33 y.o.
Essential hypertension
27w1d
506 g
+ 13w2d to 18w2d Hy 12w0d to delivery: LDA
18w2d to delivery La
7 N Patent foramen ovale/low‐lying conus medullaris 40 y.o.
Essential hypertension
35w4d
1351 g
+ 16w0d to 24w6d Me None
25w0d to delivery Me, Nif
8 N Low anorectal anomaly/low‐lying conus medullaris 42 y.o.
Essential hypertension
26w0d
379 g
+ 21w0d to 21w1d Me None
21w2d to delivery Me, Am
9 N Low‐lying conus medullaris 37 y.o.
Essential hypertension
34w3d
2108 g
16w4d to 28w5d Me None
28w6d to delivery Me, Am
10 N Potter syndrome 40 y.o.
Essential hypertension
33w6d
1836 g
None None
11 N Colpocephaly 32 y.o.
Essential hypertension
40w4d
3396 g
None None

A indicates amlodipine group; Am, amlodipine; Hy, hydralazine; La, labetalol; LDA, low‐dose aspirin; Me, methyldopa; N, No antihypertensive group; Nic, nicardipine; Nif, nifedipine; O, Other antihypertensive group; PSL, prednisolone; PVS, pulmonary valve stenosis; RA, rheumatoid arthritis; VSD, ventricular septal defect; y.o., years old.