Table 3.
Case | Group | Birth Defects | Age at Delivery/Underlying Disease | Delivery Outcome | Superimposed Preeclampsia | Antihypertensive Agents | Other Drugs | |
---|---|---|---|---|---|---|---|---|
1 | A | PVS |
41 y.o. Essential hypertension |
35w4d 1872 g |
− | Prepregnancy to 4w6d | Am | 12w0d to 28w0d: LDA |
34w5d to 35w0d | Me | |||||||
35w1d to delivery | Me, Nif | |||||||
2 | A | VSD |
36 y.o. Primary aldosteronism |
38w0d 3217 g |
− | Prepregnancy to 6w4d | Am | 8w3d to 28w0d: LDA |
6w5d to 8w0d | Hy | |||||||
8w1d to delivery | Am | |||||||
3 | O | Low‐lying conus medullaris/hypospadias/inguinal hernia |
42 y.o. Essential hypertension |
29w1d 521 g |
+ | Prepregnancy to 8w2d | La | 12w6d to delivery: LDA |
9w4d to 12w0d | Me | |||||||
12w1d to 12w5d | Me, La | |||||||
12w6d to 17w5d | Me, La, Am | |||||||
17w6d to delivery | Me, Am | |||||||
4 | O | VSD |
38 y.o. Essential hypertension RA |
25w6d 382 g |
− | Prepregnancy to delivery | Nic, La |
Prepregnancy to delivery: PSL 3w to delivery: LDA |
5 | O | Hypospadias |
39 y.o. Essential hypertension |
39w4d 2912 g |
+ | 8w4d to 30w2d | Me | None |
30w3d to delivery | Me, Am | |||||||
6 | N | Hypospadias |
33 y.o. Essential hypertension |
27w1d 506 g |
+ | 13w2d to 18w2d | Hy | 12w0d to delivery: LDA |
18w2d to delivery | La | |||||||
7 | N | Patent foramen ovale/low‐lying conus medullaris |
40 y.o. Essential hypertension |
35w4d 1351 g |
+ | 16w0d to 24w6d | Me | None |
25w0d to delivery | Me, Nif | |||||||
8 | N | Low anorectal anomaly/low‐lying conus medullaris |
42 y.o. Essential hypertension |
26w0d 379 g |
+ | 21w0d to 21w1d | Me | None |
21w2d to delivery | Me, Am | |||||||
9 | N | Low‐lying conus medullaris |
37 y.o. Essential hypertension |
34w3d 2108 g |
− | 16w4d to 28w5d | Me | None |
28w6d to delivery | Me, Am | |||||||
10 | N | Potter syndrome |
40 y.o. Essential hypertension |
33w6d 1836 g |
− | None | None | |
11 | N | Colpocephaly |
32 y.o. Essential hypertension |
40w4d 3396 g |
− | None | None |
A indicates amlodipine group; Am, amlodipine; Hy, hydralazine; La, labetalol; LDA, low‐dose aspirin; Me, methyldopa; N, No antihypertensive group; Nic, nicardipine; Nif, nifedipine; O, Other antihypertensive group; PSL, prednisolone; PVS, pulmonary valve stenosis; RA, rheumatoid arthritis; VSD, ventricular septal defect; y.o., years old.