Table 1.
Study | N | Dose (g/kg) | β60 | |
---|---|---|---|---|
| ||||
Men | Women | |||
Taylor et al. 1996 | 11 | 12 | 0.77 M; 0.67 W | M < W* |
Ammon et al. 1996 | 6 | 6 | 0.3 | M < W* |
Thomasson 1995 | 45 | 45 | 0.6 M; 0.5 W | M < W* |
Thomasson et al. 1995 | 56 | 56 | 0.54c | M < W* |
Smith et al. 1993 | 11 | 9 | 0.8 | M < W* |
Frezza et al. 1990 | 14 | 17 | 0.3 | M ~ W |
Mishra et al. 1989 | 9 | 9a | 0.6 | M < W* |
Sutker et al. 1987a | 10 | 8 | 0.50 or 0.76 | M < W* |
Cole-Harding and Wilson 1987 | 75 | 63 | 0.8d | M < W* |
Holtzman et al. 1985 | 7 | 5 | 45.0 g/day, fixed | M < W* |
Martin et al. 1985 | 194 | 208b | 0.75 | M ~ W |
Arthur 1984 | 10 | 10 | 0.5 | M ~ W |
Jones and Jones 1976a | 10 | 20 | 0.5 | M ~ W |
β60 = decrease of blood alcohol concentration (BAC) during concentration-independent phase of alcohol elimination (i.e., rate of disappearance); g/day = grams of alcohol per day; g/kg = grams of alcohol per kilogram of body weight; M = men; N = number of subjects; W = women; M < W* = significantly higher disappearance rate in women compared with men; M ~ W = no significant difference in disappearance rate.
Study compared women with their male siblings.
Total number of men and women reflect a mixture of monozygotic and dizygotic twin pairs, some same-sex pairs and some not.
Average dose; individual doses were adjusted according to a formula to produce a BAC of 0.08 percent.
Supplemental doses were administered to maintain peak BAC.
NOTE: Most of these studies show that women eliminate alcohol more quickly than men do, as measured by grams of alcohol per liter of blood per hour.