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. 1999;23(1):55–64.

Table 1.

Studies on Differences Between Men and Women in Alcohol Disappearance Rate

Study N Dose (g/kg) β60

Men Women
Taylor et al. 1996 11 12 0.77 M; 0.67 W M < W*
Ammon et al. 1996 6 6 0.3 M < W*
Thomasson 1995 45 45 0.6 M; 0.5 W M < W*
Thomasson et al. 1995 56 56 0.54c M < W*
Smith et al. 1993 11 9 0.8 M < W*
Frezza et al. 1990 14 17 0.3 M ~ W
Mishra et al. 1989 9 9a 0.6 M < W*
Sutker et al. 1987a 10 8 0.50 or 0.76 M < W*
Cole-Harding and Wilson 1987 75 63 0.8d M < W*
Holtzman et al. 1985 7 5 45.0 g/day, fixed M < W*
Martin et al. 1985 194 208b 0.75 M ~ W
Arthur 1984 10 10 0.5 M ~ W
Jones and Jones 1976a 10 20 0.5 M ~ W

β60 = decrease of blood alcohol concentration (BAC) during concentration-independent phase of alcohol elimination (i.e., rate of disappearance); g/day = grams of alcohol per day; g/kg = grams of alcohol per kilogram of body weight; M = men; N = number of subjects; W = women; M < W* = significantly higher disappearance rate in women compared with men; M ~ W = no significant difference in disappearance rate.

a

Study compared women with their male siblings.

b

Total number of men and women reflect a mixture of monozygotic and dizygotic twin pairs, some same-sex pairs and some not.

c

Average dose; individual doses were adjusted according to a formula to produce a BAC of 0.08 percent.

d

Supplemental doses were administered to maintain peak BAC.

NOTE: Most of these studies show that women eliminate alcohol more quickly than men do, as measured by grams of alcohol per liter of blood per hour.