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Effect of FK16 and Vancomycin combination in presence and absence of physiological salt concentration.
| FK16 + VCN | 0 mM NaCl | 150 mM NaCl | ||
| FIC index | Interpretationa | FIC index | Interpretationa | |
| PAO1 | 0.25 | Synergy | 0.375 | Synergy |
| PA-19660 | 0.375 | Synergy | 0.50 | Synergy |
| PA-OS | 0.375 | Synergy | 0.50 | Synergy |
aFIC Index = (MIC FK16 comb/MIC FK16 alone) + (MIC VCN comb/MIC VCN alone). FIC ≤ 0.5 represents synergy. FIC between 0.5 and 2 represents additive effect. FIC ≥ 2 represents inhibitory effect.
