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Effects of Andro on chemically induced squamous cell carcinogenesis. Hamsters were treated with saline (n = 14), 4H-Andro (n = 16), or Andro (n = 22). Andro, but not 4H-Andro, reduced tumor growth (A). Leukocyte infiltration in cancerous tissue (B). The immunohistochemical staining of BrdU (C), Tunel (D), and vWF (E) following saline, 4H-Andro, and Andro treatment. Scale bars, 20 μm for B and 50 μm for C,D,E. *p < 0.05 and **p < 0.01.
