Expression pattern of AmeloD. (A) Northern blot analysis of
AmeloD expression in different tissues from the
postnatal day 1 (P1) mouse, and the results show that
AmeloD is uniquely expressed in the mouse molars
and incisors. (B) In situ hybridization of
AmeloD expression in the embryonic day 11 (E11)
maxilla and E14, E17, and P7 mouse molars (secondary and third molars).
AS, anti-sense probe; S, sense probe. The arrow indicates the expression
of AmeloD transcript. (C)
Immunofluorescence staining of AmeloD expression with AmeloD antibody
(green) in E13.5, E14.5, E17.5, and P1 molar sections (first and second
molars). (D) Immunofluorescence staining of AmeloD with
anti-AmeloD antibody (green) in the sagittal section of the P1 mouse
incisor. The red arrows indicate the cervical loop (CL) region of mouse
incisor, and the green arrows indicate IEE cells. Scale bar: 200 µm.
(E) Quantitative polymerase chain reaction gene
expression analysis of AmeloD and
ameloblastin expression during mouse molar and
incisor development. Values are presented as mean ± SD
(n = 3). IEE, inner enamel epithelium. Am,
ameloblast.