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Diabetes induces microbial changes in a murine model. Diabetes increases IL-17 expression, leading to increased periodontal inflammation and a change in bacterial composition that is more pathogenic when transferred to a germ-free host as compared with a transfer from normoglycemic animals. Inhibition of IL-17 reduces the pathogenicity of the diabetic microbiota (for details, see Xiao et al. 2017).
