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. 2018 Nov 1;98(2):242–249. doi: 10.1177/0022034518807920

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© International & American Associations for Dental Research 2018

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Figure 3. — P2X receptors are required to mediate ATP-induced inward currents in most hDPSCs. Immunocytochemical detection of (A) P2X3 and (B) P2X7 receptors in hDPSCs. Scale bars: 20 μm. (C) P2X receptor blockade abolished ATP-induced inward currents in most hDPSCs (72%). C1: Inward current in an hDPSC induced by 3μM ATP. C2: Application of P2X receptor blocker iso-PPADS (100 μM) abolished the ATP-induced inward current. C3: After washout of P2X receptor blocker, the ATP-induced inward was reappeared. hDPSC, human dental pulp stem cell.