Table 1.
Summary of demographic, ECT, medication related variables and the estimated IST of the study subjects who underwent BP-BL ECT after anesthesia with sodium thiopental (N=56)
| Variables | Total (N=56) | Male (N=30) | Female (N=26) | Male vs. female p-values |
|---|---|---|---|---|
| Demographic variables | ||||
| Age (years) | 36.9±12.0* | 33.4±11.5 | 40.9±11.5 | 0.018 |
| Weight (kg) | 70.6±18.1 | 79.7±16.0 | 60.2±14.5 | <0.001 |
| Height (cm) | 165.5±8.5 | 171.6±4.9 | 158.4±5.8 | <0.001 |
| BMI (kg/m2) | 25.6±5.5 | 27.1±5.4 | 24.0±5.3 | 0.035 |
| Duration of illness (years) | 12.2±7.8 | 12.5±7.9 | 11.8±7.8 | 0.729 |
| ECT variables | ||||
| Thiopental dose (mg) | 214.7±62.5 | 240.8±59.3 | 184.6±52.5 | <0.001 |
| Thiopental dose/weight (mg/kg) | 3.1±0.6 | 3.0±0.5 | 3.1±0.7 | 0.725 |
| IST (millicoulomb) | 105.9±54.5 | 115.2±59.9 | 95.2±46.3 | 0.174 |
| Concomitant medications | ||||
| Chlorpromazine-equivalent dose of antipsychotics (mg) | 667.2±458.6 | 695.6±430.8 | 634.4±495.3 | 0.623 |
| Clozapine use (yes/no) | 40/16 | 20/10 | 20/6 | 0.102 |
| Anticonvulsant use (yes/no) | 27/29 | 16/14 | 11/15 | 0.579 |
| Antidepressant use (yes/no) | 14/42 | 8/22 | 6/20 | 1.000 |
| Benzodiazepine use (yes/no) | 39/17 | 16/10 | 23/7 | 0.349 |
*
numbers are expressed as mean±standard deviation or as the frequency of yes/no. The difference between male and female subjects was statistically tested with Student t-tests for continuous variables and chi-square test for dichotomous variables.
ECT: electroconvulsive therapy, IST: initial seizure threshold, BP-BL: Brief-pulse Bilateral, BMI: body mass index