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. Author manuscript; available in PMC: 2020 Jan 8.
Published in final edited form as: Nat Struct Mol Biol. 2019 Jul 8;26(8):671–678. doi: 10.1038/s41594-019-0257-3

Figure 1. The architecture of the substrate-bound spastin hexamer in a split lock-washer conformation.

Figure 1.

(a) Top (Left) and side view (Right) of the EM map of the spastin hexamer with individual protomers colored separately. Substrate density is colored in light green. The ~35 Å gap between protomer A and F is apparent in the sideview. (b) Top (Left) and side view (Right) of the atomic model in ribbon representation. Nucleotides are depicted as space-filling models and the polyglutamate peptide substrate is shown in surface representation.