Table 4.

Association between COPI genetic variants and gene expression in AD brain tissues.

SNP	EA	β	P value	PROBE	Gene	Tissue
rs11650615	G	−0.049	0.168	ILMN_1667361	COPZ2	AD cerebellar
rs9898218	T	0.009	0.787	ILMN_1667361	COPZ2	AD cerebellar
rs11650615	G	−0.017	0.701	ILMN_1667361	COPZ2	AD temporal cortex
rs9898218	T	−0.008	0.850	ILMN_1667361	COPZ2	AD temporal cortex
rs9898218	T	−0.005	0.787	ILMN_1739450	NFE2L1	AD cerebellar
rs11650615	G	−0.004	0.851	ILMN_1739450	NFE2L1	AD cerebellar
rs11650615	G	−0.019	0.389	ILMN_1739450	NFE2L1	AD temporal cortex
rs9898218	T	−0.014	0.510	ILMN_1739450	NFE2L1	AD temporal cortex
rs498872	A	0.033	0.264	ILMN_1666819	PHLDB1	AD cerebellar
rs498872	A	−0.068	0.068	ILMN_1666819	PHLDB1	AD temporal cortex

EA, effect allele; NEA, noneffect allele; β, overall estimated effect size for the effect allele.