Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Sep 19;13:991. doi: 10.3389/fnins.2019.00991

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Falasconi, Biagioni, Novelli, Piano, Gargini and Strettoi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Impairment of scotopic and photopic retinal function. (A) Representative scotopic flash ERG recordings from WT and rd9 mice in response to a flash intensity of 377.2 cd^∗s/m², the highest used for all experiments. (B) Scotopic a-wave and b-wave amplitude as a function of flash intensity from WT and rd9 mice. Both a-wave and b-wave amplitudes are significantly reduced in rd9 mutants. (C) Scotopic oscillatory potentials amplitude (OP1-OP4) extracted from ERG response to the bright test flash (377 cd^∗s/m²). (D) Representative photopic flash ERG recordings from WT and rd9 mice in response to a flash intensity of 377 cd^∗s/m² superimposed on steady background of 30 cd/m². (E) Photopic b-wave amplitude as a function of flash intensity. Cone function is significantly reduced in rd9 mice. The graph shows all the luminances used in the photopic ERG protocol, corresponding to medium and high intensity luminances also used in the scotopic ERG, but superimposed on fixed background of 30cd/m². (F) Photopic oscillatory potentials (OP1-OP4) extracted from the ERG response to the bright test flash (377 cd^∗s/m²). OPs show significantly lower amplitudes in rd9 mutants compared to WT mice. ^∗∗for p < 0.005, ^∗for p < 0.05.