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. 2019 Sep 19;9:915. doi: 10.3389/fonc.2019.00915

Table 5.

Summary of contouring guidelines for GTV, CTV, and PTV in spinal stereotactic radiosurgery.

Target volume Guidelines
GTV
  • Contour gross tumor using all available imaging

  • Include epidural and paraspinal components of the tumor

CTV
  • Include abnormal marrow signal suspicious for microscopic invasion

  • Include bony CTV expansion to account for subclinical spread

  • Should contain GTV

  • Circumferential CTVs encirclincg the cord should be avoided except in rare instances were the vertebral body, bilateral pedicles/lamina, and spinous processes are all involved or when there is extensive metastatic disease along the circumference of the epidural space without spinal cord compression

PTV
  • Uniform expansion around the CTV

  • CTV to PTV margins <3 mm

  • Modified dural margin adjacent critical structures to allow spacing at discretion of the treating physician unless GTV compromised

  • Never overlaps with cord

  • Should contain entire GTV and CTV

CTV, clinical target volume; GTV, gross tumor volume; PTV, planning target volume. From Cox et al. (62).