Table 4.

Significant and novel genes identified by aSPU with the ‘E + G + Methyl’ approach, but not by the SPU(1) and SPU(2) with ‘E + G + Methyl’, STD, ‘E + G’ and TWAS based on the SCZ2 data

		#	#
Gene	CHR	mQTL	CpG	SPU(1)	SPU(2)	aSPU	References
Source: Hippo
TCEA3	1	20	4	$7.5\times {10}^{-1}$	$9.3\times {10}^{-3}$	$1.4\times {10}^{-6}$
TRAPPC3	1	4	2	$6.9\times {10}^{-5}$	$1.4\times {10}^{-5}$	$3.7\times {10}^{-6}$	[1]
TTLL7	1	13	3	$3.8\times {10}^{-2}$	$4.8\times {10}^{-5}$	$4.0\times {10}^{-7}$
C6orf195	6	45	10	$1.0\times {10}^{-2}$	$2.0\times {10}^{-5}$	$4.8\times {10}^{-6}$
PRH1	12	183	18	$2.6\times {10}^{-2}$	$1.1\times {10}^{-4}$	$1.0\times {10}^{-7}$
FLYWCH1	16	61	13	$3.0\times {10}^{-1}$	$2.3\times {10}^{-2}$	$1.0\times {10}^{-7}$

Note: ‘sig SNP’ gives the P-value of the most significant SNP within a ± 500 kb extension for each gene in the SCZ2 data; the previously reported gene-SCZ associations appear in ‘Reference’: [1] Goes et al. (2015).