Table 4. Multivariable-adjusted linear regression analysis showing infants’ developmental outcome scores by vitamin D deficient (<50 nmol/) and sufficient (≥50 nmol/) groups.
Developmental Tests | B ±SE (95% CI) | P value | |
---|---|---|---|
Subtests | |||
Bayley | - Cognitive composite score | -0.84±1.71 (-4.21, 2.52) | 0.62 |
- Motor composite score | -0.65±1.97 (-4.54, 3.25) | 0.74 | |
- Language composite score | -2.32±1.82 (-5.92, 1.27) | 0.20 | |
- Socio-emotional composite score | -0.29±2.32(-4.88, 4.29) | 0.90 | |
Temperament | - Activity | 1.64±0.78 (0.10, 3.18) | 0.037 |
- Positive emotion | 0.51±0.58 (-0.64, 1.66) | 0.38 | |
- Negative emotion | -0.75±0.94 (-2.61, 1.11) | 0.43 | |
- Soothability | 2.02±0.70(0. 64, 3.41) | 0.004 | |
- Soothability (log transformed) | 0.03±0.01(0. 008, 0.05) | 0.007 | |
- Sociability | 0.85±0.63 (-0.38, 2.09) | 0.18 | |
- Attention | -0.35±0.66 (-1.65,0.96) | 0.60 | |
- Attention (log transformed) | -0.02±0.02 (-0.06,0.02) | 0.39 | |
CDI | - Language comprehension | 1.28±0.62 (0.05, 2.51) | 0.042 |
- Language expression | -0.02±0.17 (-0.32,0.36) | 0.91 | |
Behavior | - Approach during test | 0.02±0.12 (-0.21, 0.25) | 0.86 |
- Activity during test | 0.33±0.16 (0.02, 0.64) | 0.035 | |
- Emotional tone during test | 0.10±0.14(-0.17, 0.38) | 0.45 | |
- Cooperativeness during test | 0.06±0.12 (-0.18, 0.30) | 0.63 | |
- Vocalization during test | 0.28± 0.21 (-0.14, 0.70) | 0.19 |
Intervention effect B is the regression coefficient and SE is the Standard Error. Ranges shown are 95% CIs. Data were assessed in 58 infants in the vitamin D deficient (<50 nmol/L = 1) group versus 147 children in the vitamin D sufficient (≥50nmol = 2) group; these results were adjusted for the age of the child during assessment, asset score, maternal education, amount of stimulation received at home, height for age Z score (measured at the time of test between 7–8 months) and head circumference at 7 months