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. 2019 Sep 26;14(9):e0221805. doi: 10.1371/journal.pone.0221805

Table 4. Multivariable-adjusted linear regression analysis showing infants’ developmental outcome scores by vitamin D deficient (<50 nmol/) and sufficient (≥50 nmol/) groups.

Developmental Tests B ±SE (95% CI) P value
Subtests
Bayley - Cognitive composite score -0.84±1.71 (-4.21, 2.52) 0.62
- Motor composite score -0.65±1.97 (-4.54, 3.25) 0.74
- Language composite score -2.32±1.82 (-5.92, 1.27) 0.20
- Socio-emotional composite score -0.29±2.32(-4.88, 4.29) 0.90
Temperament - Activity 1.64±0.78 (0.10, 3.18) 0.037
- Positive emotion 0.51±0.58 (-0.64, 1.66) 0.38
- Negative emotion -0.75±0.94 (-2.61, 1.11) 0.43
- Soothability 2.02±0.70(0. 64, 3.41) 0.004
- Soothability (log transformed) 0.03±0.01(0. 008, 0.05) 0.007
- Sociability 0.85±0.63 (-0.38, 2.09) 0.18
- Attention -0.35±0.66 (-1.65,0.96) 0.60
- Attention (log transformed) -0.02±0.02 (-0.06,0.02) 0.39
CDI - Language comprehension 1.28±0.62 (0.05, 2.51) 0.042
- Language expression -0.02±0.17 (-0.32,0.36) 0.91
Behavior - Approach during test 0.02±0.12 (-0.21, 0.25) 0.86
- Activity during test 0.33±0.16 (0.02, 0.64) 0.035
- Emotional tone during test 0.10±0.14(-0.17, 0.38) 0.45
- Cooperativeness during test 0.06±0.12 (-0.18, 0.30) 0.63
- Vocalization during test 0.28± 0.21 (-0.14, 0.70) 0.19

Intervention effect B is the regression coefficient and SE is the Standard Error. Ranges shown are 95% CIs. Data were assessed in 58 infants in the vitamin D deficient (<50 nmol/L = 1) group versus 147 children in the vitamin D sufficient (≥50nmol = 2) group; these results were adjusted for the age of the child during assessment, asset score, maternal education, amount of stimulation received at home, height for age Z score (measured at the time of test between 7–8 months) and head circumference at 7 months