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. 2001 Feb 15;21(4):1257–1264. doi: 10.1523/JNEUROSCI.21-04-01257.2001

Fig. 1.

Fig. 1.

Immunohistochemical localization of neuregulin and ErbB2 in the cerebrum of an 8-week-old rat. An antibody against neuregulin-β (A–C) or an antibody against ErbB2 (D–F) was used to stain paraformaldehyde-fixed thin sections. Immunolocalization of neuregulin (A) and ErbB2 (D) in the CA1 area of the hippocampus is shown. The distribution of neuregulin (B) and ErbB2 (E) in the cerebral cortex is also shown. Most neuregulin and ErbB2 immunoreactivities appear on neuronal cell surfaces. A higher magnification of immunostained sections shows the presence of neuregulin (C) and ErbB2 (F) on cortical neuronal cells. Scale bars:A,C,D,F, 50 μm; B,E, 500 μm.