Fig. 7.
Effect of ACPD application on response mode. The cell has initially been hyperpolarized to −70 mV (horizontal dashed lines in all traces) so thatIT is de-inactivated. In the slower time base (top trace), responses to current injection are shown, and three of these (a–c) are shown at a faster time base in the bottom traces. Fora, before ACPD application, and c, after the membrane has returned to its previous hyperpolarized level, the response is in burst mode with LTSs. For b, after the ACPD has depolarized the cell, the response is in tonic mode. Notice that, during the transition from burst to tonic mode after ACPD application, no LTS was activated.