Fig. 1.

A, Varied androgen receptor distribution in the SNB of the tfm mosaic, as revealed by AR ICC without Nissl counterstain. Open arrowindicates a wild-type motoneuron exhibiting dense nuclear androgen receptor ICC label. Filled arrows indicatetfm-affected motoneurons, identifiable by their lack of nuclear androgen receptor label; the nucleoli are visible and mark the location of the nuclei. In wild-type animals, virtually all SNB motoneurons exhibit the wild-type pattern of dense nuclear AR immunolabeling. Scale bar, 50 μm. B, Nissl counterstain of AR ICC material permits measurement of the somata of SNB cells with (open arrow) or without (filled arrows) nuclear AR. Scale bar, 100 μm.