Fig. 5.

Region-specific expression of human apoE mRNA in transgenic mouse brains after in situ hybridization. Tissue sections from the brains of HEG.LE1 transgenic mice were analyzed by dark-field (A, B, C) or bright-field (D) microscopy. A, B, Olfactory bulb at 10× and 50× magnification. ON, Olfactory neuronal layer; Glo, glomerular layer; EP, external plexiform layer. C, D, Molecular and granular layers of the cerebellum at 50× and 100× magnification. BG, Bergmann glia nuclei; P, Purkinje cell nuclei.