Ataxia in fz4(−/−) mice.A, B, Hind footprints from adultfz4(+/−) and fz4(−/−) mice.fz4(−/−) mice exhibit a shortened stride, minimal alternation between the left and right feet, and frequent failures to fully lift each foot between steps. C,fz4(−/−) adults shows a wide stance, as evident in the position of the hind feet. As seen here, older animals also have a characteristic hunchback posture.