Paired-pulse facilitation is normal in the CA1 region of APP695SWE Tg mice. A, Example traces taken from 18-month-old Wt (●) and Tg (○) animals showing paired-pulse facilitation at interstimulus intervals of 25 and 100 msec. Calibration: 0.5 mV, 20 msec. B, Pooled data for 12-month-old animals (Wt, n = 34 slices from 17 animals; Tg, n = 43 slices from 16 animals).C, Pooled data for 18-month-old animals (Wt,n = 18 slices from 6 animals; Tg,n = 11 slices from 4 animals).