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A–C, Axons from ACR-injected (50 mg · kg−1 · d−1 for 18 d) T mice tibial nerves. Typical pathological lesions induced by ACR include accumulations of mitochondria, dense bodies, and other membrane-bound vesicles (arrows), vacuole formation (asterisks), and multilaminar bodies (arrowheads) of both myelinated and unmyelinated axons. Abnormal axoplasm is also found within glial compartments (C). Neurofilament accumulations were not observed. A–C, 21,500×. Scale bars, 1 μm.
