Fig. 5.

Baseline characterization of the patterns of locomotor activity. The DAT (+/+) mouse (left panel) explored all parts of the video-tracker enclosure and engaged in both circumscribed and straight movements, particularly near the corners of the enclosure. In contrast, the DAT (−/−) mouse (right panel) engaged in repetitive straight movements along the walls of the enclosure and rarely ventured into the center region. The DAT (+/−) mouse (center panel) showed a pattern that contained elements of occasional meandering and circumscribed movements and some repetitive straight movements in the periphery of the enclosure. Each pattern was reconstructed from a representative mouse from each genotype using the first 5 min of data.