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Effects of 0.1 mg/kg raclopride on spatiald and amount of locomotor activity. A, In the female mice, the movement patterns of DAT (−/−) mice were not affected by pretreatment with the D2 antagonist raclopride.B, The amount of locomotor activity was significantly reduced, however, in the DAT (−/−) mice pretreated with raclopride in blocks 1 and 2 (*p < 0.05, **p< 0.01), while having no effect in either the DAT (+/+) or (+/−) mice. Values represent means ± SEM for six 5 min blocks.
