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Effects of 0.01 mg/kg SCH23390 on spatiald and amount of locomotor activity. A, In the male mice, the D1 antagonist SCH23390 significantly attenuated the perseverative motor patterns displayed by the DAT (−/−) mice across the test session (**p < 0.01). B, D1 receptor antagonism also reduced the amount of locomotor activity in the DAT (−/−) mice in blocks 2–6 (**p < 0.01). Values represent means ± SEM for six 5 min blocks.
