Fig. 2.

Representative autoradiograms showing the modulation of 2 nm [³⁵S]TBPS binding by GABA in the dorsal hippocampus. In A, incubation buffer included no exogenous GABA; in B, 2.0 μm GABA; in C, 5 μm GABA. InA, CA1–CA3 in Ammon's horn and dentate gyrus are indicated with arrows pointing to the pyramidal or granule cell layers. In B, note the effect of GABA on [³⁵S]TBPS binding: an increase in (CA1) stratum oriens (white arrow) and a decrease in stratum radiatum (black arrow), relative to control binding inA. [³⁵S]TBPS binding was inhibited in all regions by 5 μm GABA.