Fig. 3.
Effect of CORT on the modulation of [35S]TBPS binding by GABA in the dorsal hippocampus. Experiment 2 used brain sections from gonadally intact CORT- or vehicle-treated animals incubated with 2.3 [35S]TBPS, with or without 1.5 μmGABA. Data are expressed as the specific binding of [35S]TBPS, percentage of binding in the presence of GABA relative to basal binding in the absence of GABA. Shown are means and error bars representing SEM; n = 9. There was an overall significant main effect of CORT versus vehicle treatment in hippocampus (F(1,16) = 4.80; p = 0.044), indicated by anasterisk. Set C contrasts indicated significant differences in the mean levels of modulation of [35S]TBPS binding by GABA, averaged across treatments, between CA3 radiatum and CA3 oriens (t= −13.56; p ≤ 0.0001), and between CA3 radiatum and CA1 radiatum (t = 5.15; p≤ 0.0001).