Table 1.
C/EBP mRNA and protein levels after inhibitory avoidance training
| 0 hr | 3 hr | 6 hr | 9 hr | 20 hr | 28 hr | 48 hr | 72 hr | 1 week | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| − | − | + | − | + | − | + | SO | − | + | SO | − | + | − | + | − | + | − | + | |
| mRNA | |||||||||||||||||||
| C/EBPβ | 100 ± 4.8 | 98.0 ± 5.4 | 94.0 ± 16.5 | 88.5 ± 9.8 | 86.1 ± 7.0 | 105.6 ± 8.1 | 144.5 ± 11.8 | 90.8 ± 6.9 | 101.9 ± 4.3 | 196.0 ± 20.1 | 100.6 ±3.5 | 112.8 ± 10.4 | 104.1 ± 12.3 | 97.3 ± 7.2 | 78.6 ± 7.1 | ||||
| p | <0.01 | <0.01 | |||||||||||||||||
| CEBPδ | 100 ± 3.6 | 88.1 ± 2.8 | 107.8 ± 12.4 | 96.0 ± 17.4 | 111.3 ± 4.5 | 110.1 ± 17.2 | 105.9 ± 3.7 | 109.9 ± 17.2 | 92.4 ± 5.8 | 146.6 ± 14.6 | 99.1 ± 1.9 | 102.1 ± 3.3 | 100.2 ± 7.8 | 93.5 ± 5.6 | 88.0 ± 5.6 | ||||
| p | <0.01 | ||||||||||||||||||
| Protein | |||||||||||||||||||
| C/EBPβ | 100 ± 4.2 | 90.2 ± 3.4 | 127.3 ± 3.6 | 110.4 ± 3.0 | 159.7 ± 6.6 | 104.1 ± 6.1 | 154.8 ± 11.9 | 111.3 ± 1.8 | 90.7 ± 6.1 | 109.2 ± 4.2 | 106.7 ± 3.5 | ||||||||
| p | <0.05 | <0.01 | <0.01 | ||||||||||||||||
Concentrations are expressed as mean percentage ± SEM of the 0 hr − (100%) control mean values. Groups of animals were fully trained (+), entered the training apparatus without receiving foot shock (−), or received the shock without exposure to the apparatus [shock only (SO)] and killed at assigned time points. Concentrations are expressed as mean percentage ± SEM of the 0 hr − (100%) control mean values. Groups of animals were fully trained (+), entered the training apparatus without receiving foot shock (−), or received the shock without exposure to the apparatus [shock only (SO)] and killed at assigned time points.